By Dr. Angela DeRosa
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October 15, 2025
What if I told you that replenishing your naturally declining hormones could have a significant positive impact on your heart health? Or protect your bones from osteoporosis? What if a steady supply of hormones as you age could reduce your risk of certain diseases, like breast cancer? Would you consider replacing your hormones then? I begin this article with these little-known facts about bioidentical hormone replacement therapy (BHRT), because I’m guessing nobody (especially not your primary care physician or your gynecologist) is telling you about the numerous potential benefits of BHRT. It’s not their fault; they were never properly taught about perimenopause, menopause, and hormone therapies in medical school. And, the research about the benefits of hormone therapies hardly becomes part of mainstream medical information or our culture. So, I want to answer this question about why you should replace your hormones, for you and for all the women who are struggling through perimenopause, menopause, postmenopause. “There is plenty of data supporting hormone replacement therapy and its health benefits - most [physicians] just haven’t bothered to read it or learn it.” – Angela DeRosa, DO, MBA, CPE Perhaps you’re gaining weight you can’t lose; losing sleep because of hot flashes and racing thoughts; and contemplating divorce because your libido tanked and you frequently have to resist the urge to strangle your husband/significant other. These reasons alone are grounds for BHRT, but the added health benefits to your heart, bones, and overall wellness, should make the answer to this personal question quite obvious. Uncertainty Often Surrounds BHRT Maybe you feel uncertain about BHRT, like many women, because you’ve heard conflicting messages about hormone therapy over the years. Unfortunately, the flawed Women’s Health Initiative (WHI) study from the late 90s, instilled panic in the perimenopausal population. However, more than 20 years later, the original WHI study was finally brought to light as flawed . They used synthetic hormones and the majority of women in the study were more than 10 years past menopause! This is hardly the target demographic for BHRT candidates, and bioidentical hormones are not synthetic! Bioidentical hormones are derived from plants and chemically identical to the hormones your body naturally produces.* Now we know that for most healthy women who begin BHRT around the time of perimenopause or within about 10 years after menopause (before age 60), bioidentical hormone replacement therapy can offer profound benefits, not only for symptom relief, but for long-term health, as well. Tip of the Iceberg: Relief of Menopause Symptoms Does this sound familiar? As you’ve gotten older and your body’s natural levels of estrogen, progesterone, and testosterone decline, you began experiencing: Hot flashes and night sweats Mood swings, irritability, or anxiety Poor sleep and fatigue Brain fog or memory lapses Vaginal dryness and discomfort Painful sex Low libido Clearly, these symptoms can affect how you feel every day, and in some cases, make you downright miserable. BHRT helps restore hormones to a healthy, more youthful balance, often reducing symptoms within weeks. Many women begin sleeping better, feeling more energized, and noticing improved moods and mental clarity. Beyond Symptom Relief: Long-term Benefits of Hormone Therapy Now, let’s get to the long-term benefits of BHRT. Hormones don’t just affect how you feel; they play a key role in so many systems in your body. Replacing hormones during midlife may support your long-term health in ways you don’t even realize. Heart Health Estrogen helps keep blood vessels flexible and supports healthy cholesterol, while testosterone helps optimize glucose metabolism, and prevent its intolerance. If your testosterone is too low, it can lead to insulin resistance, making it harder for your body to absorb blood sugar. Studies suggest that when started within 10 years of menopause, hormone therapy may reduce the risk of heart disease, the leading cause of death in postmenopausal women. Bone Strength Estrogen helps maintain bone density. Without it, your bones can weaken faster, increasing your risk of fractures. BHRT can slow bone loss and reduce the risk of osteoporosis-related fractures. Sexual and Urinary Wellness Estrogen is vital for maintaining vaginal and urinary tract tissue health. Restoring it can ease dryness, improve comfort during intimacy, and help reduce urinary frequency or urgency. Plus, testosterone affects clitoral sensitivity and ability to orgasm. Prolonged levels of low testosterone in women usually leads to lack of desire and avoiding sex because it’s too painful and no longer a pleasurable experience. Research indicates a myriad of benefits from having sex regularly, including lower stress, less risk of diseases, better sleep, and increased longevity. Women who have sex at least once a week live longer than women who rarely have sex! Brain and Mood Support When your hormones are balanced, you’ll likely feel more focused, have more even-keeled moods, and experience improved memory and cognitive functions (forgetting words less is a wonderful thing). Potential Cancer Protection Contrary to common fears (most of which were perpetrated after the WHI study), certain BHRT regimens are linked to a lower risk of breast cancer compared to women who never use hormone therapy. So, are you feeling less apprehensive about considering bioidentical hormone replacement therapies that are personalized just for you? Not sure where to start? The best thing you can do is educate yourself, so you can ask the right questions when you speak to your healthcare practitioner. As someone who has treated more than 20 thousand patients in the last 30 years, and written about BHRT, you might find my book, A Woman’s Hormonal Health Survival Guide: How to Prevent Your Doctor from Slowly Killing You , a helpful tool in your perimenopause journey and beyond. *Read more about synthetic vs. bioidentical hormones in Chapter 2: CHALLENGES, MYTHS AND MISCONCEPTIONS ABOUT HRT Check out Chapter 9: YOUR HEALTH SURVIVAL GUIDE CHECKLIST to see if hormone therapy is right for you.